Juan Sanchez-Ramos, MD, PhD

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Dr. Sanchez-Ramos received a Ph.D. in Pharmacology and Physiology from the University of Chicago and a medical degree (M.D.) from the University of Illinois. His PhD thesis work focused on the mechanisms of opiate dependence in monkey models. He trained in Neurology at the University of Chicago and as a Fellow in Movement Disorders at the University of Miami. Currently, he is a Professor of Neurology at the University of South Florida in Tampa where he holds the Helen Ellis Endowed Chair for Parkinson’s Disease Research and is Director of the HDSA Center of Excellence for Huntington’s Disease. In addition to teaching and attending to patients with Movement Disorders, he directs a basic research laboratory with active projects in neurodegeneration, neurotoxicology and adult stem cell biology. He is also Medical Director of the Parkinson Research Foundation based in Sarasota FL. He has a long-standing interest in ethnopharmacology and has published on the use of banisterine in the treatment of Parkinson’s disease, collaborated on research on the possible medicinal applications of ibogaine and was an Investigator in the NIDA-sponsored compassionate use of Cannabis protocol.

Publications: Over 300 scientific articles (includes original research, chapters, published abstracts and letters).

Selected publications related to drug dependence and medical application of agents with long histories of traditional use

Sanchez-Ramos, J. and Schuster, C.R. Second Order schedules of intravenous drug self-administration in the rhesus monkey. Pharm. Biochem. Behav. 7:443-450, 1977

Stretch, R. and Sanchez-Ramos, J.Effects of morphine, naloxone, and diallylnormorphine upon behavior maintained by electric shock postponement in squirrel monkeys. Can. J. Physiol. Pharmacol. 57: 98-105, 1979

Sanchez-Ramos, J. and Senay, E. Ophthalmic naloxone elicits abstinence in opioid-dependent subjects. Brit. J. Addict., 82:313315, 1986

Mash, D.C., Douyon, R., Hearn, W.L., Sambol, N.C. and Sanchez-Ramos, J. A Preliminary Report on the Safety and Pharmacokinetics of Ibogaine. Biol Psychiat 37:652, 1995
Sanchez-Ramos, J. Banisterine and Parkinson’s Disease. Clinical Neuropharm 14:391-402, 1991

Mash DC, Kovera CA, Buck BE, Norenberg MD, Phapshak P, Hearn WL, Sanchez-Ramos J. Medication development of ibogaine as a pharmacotherapy for drug dependence. In. The Neurology of Drugs of Abuse Cocaine, Ibogaine and Substituted Amphetamines (Ed. Syed Ali) Annals NY Acad Sci, 275-292, 1998

Sanchez-Ramos, J. and Mash D. Pharmacotherapy of drug dependence with ibogaine. In, Constructive Potentials of Psychedelics: Cross-cultural perspectives (Ed) M. Winkelman, W Andritzky). Yearbook of Cross-Cultural Medicine and Psychotherapy Volume 4, 1996

Serrano-Duenas M, F. Cardozo-Pelaez, J. Sanchez-Ramos. Effects of Banisteriopsis Extracts on De Novo Parkinson’s Disease Patients. Scientific Rev of Alternative Medicine 3:127-132, 2001

Russo E, Mathre ML, Byrne A, Velin R, Bach PJ, Sanchez-Ramos J, and Kirlin KA. Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis. Journal of Cannabis Therapeutics, 2(1): 3-57, 2002

Catlow BJ, Badanich KA, Sponaugle AE, Rowe AR, Song S, Rafalovich I, Sava V, Kirstein CL, Sanchez-Ramos J. Effects of MDMA (“ecstasy”) during adolescence on place conditioning and hippocampal neurogenesis. Eur J Pharamcol 628:96-103, 2009

Briony Catlow, Shijie Song, Daniel Paredes, Cheryl Kirstein and J. Sanchez-Ramos Effect of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Exp. Brain Research (2013) 228:481–491 DOI: 10.1007/s00221-013-3579-0

O’Neill C and Sanchez-Ramos J. Cannabinoids for the treatment of Movement Disorders in The Pot Book edited by Julie Holland MD. 2013 http://www.thepotbook.com/potbook/additional_chapters.html

Benbadis, S.R., Sanchez-Ramos, J., Bozorg, A., Giarratano, M., Kalidas, K., Katzin, L., Robertson, D., Vu, T., Smith, A. and Zesiewicz, T. (2014). Medical marijuana in neurology. Expert review of neurotherapeutics 14, 1453-1465.

Catlow, B. and Sanchez-Ramos, J. (2015). Cannabinoids for the Treatment of Movement Disorders. Current treatment options in neurology 17, 370.

Sanchez-Ramos, J. (2015). Neurologic Complications of Psychomotor Stimulant Abuse. International review of neurobiology 120, 131-160.

Sanchez-Ramos, J. (2015). The entourage effect of the phytocannabinoids. Ann Neurol 77, 1083.

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